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TRANSFORMING GROWTH FACTORS
Descriptors Found:
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DeCS
Descriptor
English
:
Transforming Growth Factors
Descriptor
Spanish
:
Factores de Crecimiento Transformadores
Descriptor
Portuguese
:
Fatores de Crescimento Transformadores
Tree Number:
D12.644.276.954.800
D12.644.276.963
D12.776.467.942.800
D12.776.467.960
D23.529.942.800
D23.529.960
Definition
English
:
Hormonally active polypeptides that can induce the transformed
phenotype
when added to normal, non-transformed
cells
. They have been found in
culture
fluids from retrovirally transformed
cells
and in tumor-derived
cells
as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors,
TRANSFORMING GROWTH FACTOR ALPHA
and
TRANSFORMING GROWTH FACTOR BETA.
Indexing Annotation
English
:
general or unspecified; prefer specifics
History Note
English
:
89
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23851
Unique Identifier:
D015291
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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